gene regulation

Gene Regulation and Interference in Developing Chicken Inner Ear

鸡内耳发育的基因调控与干预

Intronic mutations may affect gene regulation through aberrant splicing or disruption of critical DNA protein interactions.

内含子突变可以通过引起剪接异常或关键性DNA-蛋白反应中断而影响基因调控。

Histone deacetylase inhibitor ( HDACi) has been shown to demethylate mammalian genome, which further strengthens the concept that DNA methylation and histone modifications interact in regulation of gene expression.

已有报道证实组蛋白去乙酰化酶抑制剂（HDACi）可以引起哺乳动物基因组的去甲基化，这支持了DNA甲基化和组蛋白修饰可以相互作用调节基因的表达的观点。

Plasmid DNA has important function of gene regulation, direct injection of naked or Lipid-coated plasmid DNA often requires considerable amount of plasmid DNA.

质粒DNA有重要的基因调节性能，直接注射裸露或用脂质体包埋的质粒DNA常需要大量的质粒DNA。

Modeling of the Gene Regulation Network with a Systems Biology Approach

基因调控网络的系统生物学建模

In view of the light characteristics of gene regulation, cluster genes by use of correlation clustering, and then model the mutual regulation of genes in one cluster with the state-space model.

针对基因调控的稀疏子模块特点，先利用相关性聚类对基因进行分解，得到多个基因簇，然后利用状态空间方程对每个簇的基因间相互调控关系进行建模分析。

The gene regulation networks can help biologists know more about the systematical biological phenomena.

基因调节网路可以帮助生物学家了解更多系统性的生物现象.

Methylation of CpG Islands is one of the most important mechanisms in the epigenetic regulation of gene expression.

CpG岛的甲基化是表观遗传中基因表达调控的重要机制。

Use of genetic Methods: To analyze protein function, gene regulation and inherited disease.

以及运用遗传学的方法分析蛋白质的功能 、 基因的调控与遗传性的疾病.

Research on the model organism Drosophila indicate that insect AMPs gene regulation involves multiple signaling pathways and a large number of signaling molecules.

以果蝇为模式生物研究表明，昆虫抗菌肽的基因调控涉及到多个信号通路及大量的信号分子。

The Cell Pattern Construction of Human apoA-I Gene Regulation and Secretory Expression

人apoA-I分泌型表达调控细胞模型构建

Zine finger proteins are important and typical Proteins for gene regulation.

锌指蛋白是重要的、典型的基因调控蛋白.

This paper summarizes about caste determination of social insect concerning gene regulation, These may offer some useful information for the correlative study.

文章对社会性昆虫品级分化相关基因的研究概况作一综述，以期对以后相关方面的深入研究有所帮助。

This gene regulation is accomplished by epigenetic processes that control gene expression without altering DNA.

这是基因调控是由控制基因的表观遗传完成的，并没有改变DNA。

This means that in the mutant the changes of the protein level during albinic stage might be related to gene regulation at the transcription level.

可能返白系在返白期间蛋白质水平的变化与转录水平的基因调控有关。

Eukaryotic gene regulation can alos occur at the level of translation.

真核基因调控也可以发生在翻译水平.

The iNOS gene knock-down research showed that AS-ODN technique was an effective way to achieve the specific regulation of iNOS expression, while it was also been confirmed that the inhibiting of inducible NO production did promote the expression of TGF-B, by GMC in vitro.

AS-ODN iNOS基因封闭研究结果证实天津医科大学博士研究生学位论文AS－ODN技术是实现iNOS特异性调控的有效方式，并且直接证实了抑制GMC诱导性NO产生可以促进TGF－6；表达。

DNA Sequence motifs are becoming increasingly important in the analysis of gene regulation, and the identification of motif in DNA sequences is a hot issue in computational biology.

DNA序列模体对研究基因的表达调控有重要作用，模体识别问题是计算生物学中一个热点问题。

DNA methylation is an important epigenetic mark forthe regulation of gene expression in eukaryotes.

在真核生物中，DNA甲基化修饰是调控基因表达的一个重要的表观遗传学标志。

Research on some fungal species in recent years shows, chromosome epigenetic state is directly related to the regulation of fungal secondary metabolite gene cluster.

近年来对一些真菌物种进行的研究结果显示，染色体的表观遗传状态也直接调控真菌次生代谢相关基因簇的表达。

V-shaped Gene Regulation Model and Prediction of Gene Regulation Relationships of Eukaryotes

真核生物的V形基因调控模型和基因调控关系的预测

A gene regulation network was then built to further identify genes responsible for differential gene expression and copy number variation between the chemotherapy resistant group and the chemotherapy sensitive group.

然后建一个基因调控网络进一步查明负责化疗耐药组和化疗敏感组之间的差异表达基因的拷贝数变异的基因。

MicroRNA ( miRNA) is evolutionarily conserved, non-coding small RNA ( 19-25 nt) involved in post-transcriptional gene regulation.

microRNA（miRNA）是一组在进化上高度保守、非编码蛋白、参与转录后调节的小分子RNA（19-25核苷酸）。

Chromatin immunoprecipitation assay ( ChIP) provides a powerful tool to analyze the interaction of trans-acting factors with specific chromatin regions in vivo, as well as the role of histone modifications in gene regulation.

染色质免疫沉淀法是研究染色质结构的首选方法，它不仅可用来研究体内反式因子与DNA的相互作用，也可以用来研究组蛋白修饰与基因表达的关系。

The relationship between histone acetylation modification and IFN-gamma responsive gene regulation

组蛋白修饰与干扰素γ应答基因调控的关系

Simultaneity, with the help of text mining technology, we create the Gene Regulation Information Source DataBase ( GRIS) and Gene regulaion oriented information agent system ( InfoAgent).

同时结合文本挖掘技术分别建立了基因调控信息资源库（GRIS）和基因调控信息智能检索系统（InfoAgent）。

These fragments encode proteins involved in electron transfer and proton transport, the ubiquitin-proteasome pathway, and epigenetic gene regulation.

这些基因编码蛋白参与电子和质子转运、泛素&蛋白体途径以及表观遗传调控（epigenetic regulation）等。